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5 Panel Drug Test is competitive binding, lateral flow immunochromatographic assay for qualitative and simultaneous detection of Amphetamine, Oxazepam, Cocaine, Cannabinoids, Methamphetamine, Morphine, Oxycodone, EDDP, Secobarbital, Buprenorphine, Methylenedioxymethamphetamine, Phencyclidine, Propoxyphene , Nortriptyline and Methadone in human urine.
The test may yield positive results for the prescription drugs Buprenorphine, Oxazepam, Secobarbital and Oxycodone when taken at or above prescribed doses. It is not intended to distinguish between prescription use or abuse of these drugs. Clinical consideration and professional judgment should be exercised with any drug of abuse test result, particularly when the preliminary result is positive. The test provides only preliminary test results. A more specific alternative chemical method may be used in order to obtain a confirmed analytical result. GC/MS or LC/MS is the preferred confirmatory method. For
Product | Cat No | Specimen | Sensitivity | Format | Kit Size |
Drugs of Abuse (DOA) Tests | |||||
AMP | YD101S3 | Urine | 1000 ng/mL | 3mm Strip | 100T |
YD101C4 | 4mm Cassette | 25T | |||
BAR | YD201S3 | Urine | 300 ng/mL | 3mm Strip | 100T |
YD201C4 | 4mm Cassette | 25T | |||
BZO | YD301S3 | Urine | 300 ng/mL | 3mm Strip | 100T |
YD301C4 | 4mm Cassette | 25T | |||
COC | YD401S3 | Urine | 300 ng/mL | 3mm Strip | 100T |
YD401C4 | 4mm Cassette | 25T | |||
MOR(MOP) | YD501S3 | Urine | 300 ng/mL | 3mm Strip | 100T |
YD501C4 | 4mm Cassette | 25T | |||
MET | YD601SM | Urine | 500 ng/mL | 3mm Strip | 100T |
YD601CM | 4mm Cassette | 25T | |||
MTD | YD701S3 | Urine | 300 ng/mL | 3mm Strip | 100T |
YD701C4 | 4mm Cassette | 25T | |||
MDMA | YD801S3 | Urine | 500 ng/mL | 3mm Strip | 100T |
YD801C4 | 4mm Cassette | 25T | |||
THC | YD901S3 | Urine | 50 ng/mL | 3mm Strip | 100T |
YD901C4 | 4mm Cassette | 25T | |||
BUP | YD111S3 | Urine | 100 ng/mL | 3mm Strip | 100T |
YD111C4 | 4mm Cassette | 25T | |||
PCP | YD121S3 | Urine | 25 ng/mL | 3mm Strip | 100T |
YD121C4 | 4mm Cassette | 25T | |||
K2 | YD131S3 | Urine | 200 ng/mL | 3mm Strip | 100T |
YD131C4 | 4mm Cassette | 25T | |||
OPI | YD141S3 | Urine | 2000 ng/mL | 3mm Strip | 100T |
YD141C4 | 4mm Cassette | 25T | |||
TCA | YD151S3 | Urine | 1000 ng/mL | 3mm Strip | 100T |
YD151C4 | 4mm Cassette | 25T | |||
KET | YD161S3 | Urine | 1000 ng/mL | 3mm Strip | 100T |
YD161C4 | 4mm Cassette | 25T | |||
TML | YD171S3 | Urine | 100 ng/mL | 3mm Strip | 100T |
YD171C4 | 4mm Cassette | 25T |
If refrigerated, allow the test device to come to room temperature, 59-86°F (15-30°C) prior to testing. 1) Remove the Clarity Multi-Drug Urine Test Dip Card from the foil wrapper. 2) Fill a specimen cup (not provided) with fresh urine. Dip the Clarity Multi-Drug Urine Test Dip Card into the urine with the arrow end pointing toward the urine. Do not cover the urine over the MAX (maximum) line. You may leave the Clarity Multi-Drug Urine Test Dip Card in the urine or you may take the Dip Card out after a minimum of 15 seconds in the urine and lay the Dip Card flat on a non-absorptive clean surface. 3) Read results at 5 minutes and do not throw away the urine. Urine used may be needed for confirmation testing.
Summary:
The test is intended for use as the process to provide health care professionals and consumers with information concerning the presence or absence of the above stated drugs in a urine sample.
METHAMPHETAMINE(MET,mAMP) Methamphetamine is anaddictive stimulant drug that strongly activates certain systems in the brain. Methamphetamine is closely related chemically to amphetamine, but the central nervous system effects of Methamphetamine are greater.Methamphetamine is made in illegal laboratories and has a high potential for abuse and dependence. The drug can be taken orally, injected, or inhaled. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to Methamphetamine include increased blood pressure and cardiac arrhythmias. More acute responses produce anxiety, paranoia, hallucinations, psychotic behavior, and eventually, depression and exhaustion. The effects of Methamphetamine generally last 2-4 hours and the drug has a half-life of 9-24hoursin the body.Methamphetamine is excretedin the urineas amphetamine andoxidized and delaminated derivatives. However, 10-20% of Methamphetamine is excreted unchanged. Thus, the presenceofthe parentcompoundinthe urineindicatesMethamphetamine use.
COCAINE(COC) Cocaine is a potent centralnervous system(CNS) stimulant and alocal anesthetic. Initially, it brings about extreme energy and restlessness while gradually resulting in tremors, over-sensitivity and spasms. In large amounts, cocaine causes fever, unresponsiveness, difficulty in breathing and unconsciousness.
MORPHINE(MOP) Opiate refers to any drug that is derived from the opium poppy, including the natural products, morphine and codeine, and the semi-synthetic drugs such as heroin. Opioid is more general, referring to any drug that acts on the opioid receptor. Opioid analgesics comprise a large group of substances which control pain by depressing the central nervous system. Large doses of morphine can produce higher tolerance levels, physiological dependency in users, and may lead to substance abuse. Morphine is excreted unmetabolized, and is also the major metabolic product of codeine and heroin. Morphine is detectable inthe urineforseveral days afteranopiatedose.4
MARIJUANA(THC) THC ( 9--tetrahydrocannabinol) is the primary active ingredient in cannabinoids (marijuana). When smoked or orally administered, it produces euphoric effects. Users have impaired short term memoryand slowedlearning.They may alsoexperience transient episodes ofconfusion andanxiety. Long term relatively heavy use may be associated with behavioral disorders. The peak effect of smoking marijuana occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking. The main metabolite excreted in the urine is 11-nor- 9-tetrahydrocannabinol-9-carboxylic acid ( 9-THC-COOH).
BENZODIAZEPINES(BZO) Benzodiazepines are medications that are frequently prescribed for the symptomatic treatment of anxiety and sleep disorders. They produce their effects via specific receptors involving a neurochemical called gamma aminobutyric acid (GABA). Becausethey aresafer andmoreeffective, Benzodiazepines have replaced barbiturates in the treatment of both anxiety and insomnia. Benzodiazepines are also used as sedatives before some surgical and medical procedures, and for the treatment of seizure disorders and alcohol withdrawal. Risk of physical dependence increases if Benzodiazepines are taken regularly (e.g., daily) for more than a few months, especially at higher than normal doses. Stopping abruptly can bring on such symptoms as trouble sleeping, gastrointestinal upset, feeling unwell, loss of appetite, sweating, trembling, weakness, anxiety and changes in perception. Only trace amounts (less than 1%) of most Benzodiazepines are excreted unaltered in the urine; most of the concentration in urine is conjugated drug. The detection period fortheBenzodiazepines inthe urineis 3-7days.
OXYCODONE(OXY)
AMPHETAMINE(AMP) Amphetamine is a Schedule II controlled substance available by prescription and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural catecholamines: epinephrine and norepinephrine. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to Amphetamines include increased blood pressure and cardiac arrhythmias. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behavior. The effects of Amphetamines generally last 2-4 hours following use, and the drug has a half-life of 4-24 hours in the body.About 30% ofAmphetamines are excreted in the urinein unchangedform, withthe remainder ashydroxylated anddeaminatedderivatives. BARBITURATES(BAR) Barbiturates are central nervous system depressants. They are used therapeutically as sedatives, hypnotics, and anticonvulsants. Barbiturates are almost always taken orally as capsules or tablets. The effects resemble those of intoxication with alcohol. Chronic use of barbiturates leads to tolerance and physical dependence. Short acting Barbiturates taken at 400 mg/day for 2-3 months can produce a clinically significant degree of physical dependence. Withdrawal symptoms experienced during periods of drug abstinence can be severe enough to cause death. Only a small amount(less than5%)ofmostBarbituratesareexcretedunalteredinthe urine.
Table 3 lists the compounds that are positively detected in urine by the BAR One Step Barbiturates Test Strip (Urine) at 5 minutes and the concentrations at which they are detected.
Analytical Specificity
Compound | Concentration (ng/mL) | Compound | Concentration (ng/mL) |
Secobarbital | 300 | Butalbital | 2,500 |
Amobarbital | 300 | Butethal | 100 |
Alphenol | 150 | Cyclopentobarbital | 600 |
Aprobarbital | 200 | Pentobarbital | 300 |
Butabarbital | 375 | Phenobarbital | 100 |
Compound | Conc. (ng/mL) | Compound | Conc. (ng/mL) |
Carfentanyl | 500 | Fentanyl | 100 |
Sufentanil | 50,000 | (±)cis-3-Methylfentanyl | 20,000 |
Ramifentanil | 10,000 | Butyl fentanyl | 150 |
alpha-Pyrrolidinovalerophenone | n | Site A | Site B | Site C | |||||
Concentration (ng/mL) | per Site | - | + | - | + | - | + | ||
0 | 10 | 10 | 0 | 10 | 0 | 10 | 0 | ||
500 | 10 | 10 | 0 | 10 | 0 | 10 | 0 | ||
750 | 10 | 8 | 2 | 9 | 1 | 9 | 1 | ||
1250 | 10 | 2 | 8 | 3 | 7 | 1 | 9 | ||
1500 | 10 | 0 | 10 | 0 | 10 | 0 | 10 |