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For IVD Manufacture Mouse Anti-Oxycodone Monoclone Antibody Drug of Abuse
Background:
Oxycodone is a semi-synthetic opioid with a structural similarity to codeine. The drug is manufactured by modifying thebaine, an alkaloid found in the opium poppy. Oxycodone, like all opiate agonists, provides pain relief by acting on opioid receptors in the spinal cord, brain, and possibly directly in the affected tissues. Oxycodone is prescribed for the relief of moderate to high pain under the well-known pharmaceutical trade names of OxyContin®, Tylox®, Percodan® and Percocet®. While Tylox®, Percodan® and Percocet® contain only small doses of oxycodone hydrochloride combined with other analgesics such as acetaminophen or aspirin, OxyContin consists solely of oxycodone hydrochloride in a time-release form. Oxycodone is known to metabolize by demethylation into oxymorphone and noroxycodone. In a 24-hour urine, 33-61% of a single, 5 mg oral dose is excreted with the primary constituents being unchanged drug (13-19%), conjugated drug (7-29%) and conjugated oxymorphone (13-14%). The window of detection for Oxycodone in urine is expected to be similar to that of other opioids such as morphine.
Specification:
CONCENTRATION | 2.40 mg/mL by A280nm |
ISOTYPE | IgG-1 |
STORAGE | Short Term: Refrigerated / Long Term: Frozen |
CROSS REACTIVITY | % Cross-Reactivity at D50 ELISA Compounds Codeine 0.13 % Hydrocodone 4.2 % Hydromorphone 5.0 % Morphine 0.10 % Naloxone 0.43 %Oxymorphone 91.0 % Thebaine 0.80 % |
SPECIFICITY | Oxycodone |
LOT NUMBER | B62 |
DESCRIPTION | Purified Monoclonal Antibody |
HOST: | Murine |
BUFFER | PBS Azide |
PRESERVATIVE | 0.05% Sodium Azide |
ANTIGEN USED: | Oxycodone-BgG |
FORMAT | Protein A Purified |
ORIENT NEW LIFE MEDICAL CO., LTD. | |
Contact: | Jerry Meng |
Email: | Jerry @ newlifebiotest .com |
Tel. | +86 18657312116 |
SKYPE | enetjerry |